When Ethan Hunt, the leader of a crack espionage team whose perilous operation has gone awry with no explanation, discovers that a mole has penetrated the CIA, he’s surprised to learn that he’s the prime suspect. In order to clear his name, Hunt now must ferret out the real double agent and, in the process, even the score.

With the support of his team at his side, agent Ethan Hunt must race across Australia and Spain to stop a former IMF agent from unleashing a genetically engineered biological weapon called Chimera.

Lured back into action by his agency superiors, Ethan Hunt faces his deadliest adversary yet - a sadistic weapons dealer named Owen Davian. With the support of his IMF team, Ethan leaps into spectacular adventure from Rome to Shanghai as he races to rescue a captured agent and stop Davian from eliminating his next target: Ethan's wife, Julia.

Blamed for the terrorist bombing of the Kremlin, IMF operative Ethan Hunt is disavowed along with the rest of the agency when the President initiates "Ghost Protocol". Left without any resources or backup, Ethan must find a way to clear his agency's name and prevent another attack. To complicate matters further, Ethan is forced to embark on this mission with a team of fellow IMF fugitives whose personal motives he does not fully know.

Ethan and team take on their most impossible mission yet, eradicating the Syndicate - an International rogue organization as highly skilled as they are, committed to destroying the IMF.

Ethan Hunt and his IMF team, along with some familiar allies, race against time after a mission gone wrong.